Recurrent Miscarriage: Diagnostic and Therapeutic Procedures. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/050, May 2022)

Abstract Purpose The aim of this guideline is to standardize the diagnosis and therapy recurrent miscarriage (RM) using evidence from recent literature. This done by consistent definitions, objective evaluations standardized treatment protocols. Methods When was compiled, special consideration given previous recommendations in prior versions European Society Human Reproduction Embryology, Royal College Obstetricians Gynecologists, American Gynecologists for Reproductive Medicine, a detailed individual search literature about different topics carried out. Recommendations diagnostic therapeutic procedures offered couples with RM were developed based on international Special attention paid known risk factors such as chromosomal, anatomical, endocrinological, physiological coagulation, psychological, infectious immune disorders. also those cases where investigations are unable find any abnormality (idiopathic RM).